Article
Network-Based Analysis of eQTL Data to Prioritize Driver Mutations.
Genome biology and evolution - 23 Jan 2016
De Maeyer Dries, Weytjens Bram, De Raedt Luc, Marchal Kathleen
Abstract excerpt
In clonal systems, interpreting driver genes in terms of molecular networks helps understanding how these drivers elicit an adaptive phenotype. Obtaining such a network-based understanding depends on the correct identification of driver genes. In clonal systems, independent evolved lines can acquire a similar adaptive phenotype by affecting the same molecular pathways, a phenomenon referred to as parallelism at...
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