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Article

GRETTA: an R package for mapping in silico genetic interaction and essentiality networks.

Bioinformatics (Oxford, England) - 1 Jun 2023

Takemon Yuka, Marra Marco A

Abstract excerpt

SUMMARY: Mapping genetic interactions and essentiality networks in human cell lines has been used to identify vulnerabilities of cells carrying specific genetic alterations and to associate novel functions to genes, respectively. In vitro and in vivo genetic screens to decipher these networks are resource-intensive, limiting the throughput of samples that can be analyzed. In this application note, we provide an R...

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Identifiers

PMID: 37326978
DOI: 10.1093/bioinformatics/btad381
PMCID: PMC10284671

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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