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GRETA: an R package for mapping <i>in silico</i> genetic interaction and essentiality networks

2022-09-22

Abstract excerpt

<h4>Summary</h4> Mapping genetic interaction and essentiality networks in human cell lines have been used to identify vulnerabilities of cells carrying specific genetic alterations and to associate novel functions to genes, respectively. In vitro and in vivo genetic screens to decipher these networks are resource-intensive, limiting the throughput of samples that can be analyzed. In this application note, we pr...

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Literature Corpus work
ca848848-3188-5465-b0b1-74d0987f0114
DOI
10.1101/2022.09.21.508787
Open publication

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GRETA: an R package for mapping <i>in silico</i> genetic interaction and essentiality networksDOI 10.1101/2022.09.21.508787
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