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Article

Extracting Fitness Relationships and Oncogenic Patterns among Driver Genes in Cancer.

Molecules (Basel, Switzerland) - 25 Dec 2017

Zhang Xindong, Gao Lin, Jia Songwei

Abstract excerpt

Driver mutation provides fitness advantage to cancer cells, the accumulation of which increases the fitness of cancer cells and accelerates cancer progression. This work seeks to extract patterns accumulated by driver genes ("fitness relationships") in tumorigenesis. We introduce a network-based method for extracting the fitness relationships of driver genes by modeling the network properties of the "fitness" of...

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Identifiers

PMID: 29295608
DOI: 10.3390/molecules23010039
PMCID: PMC5943933

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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