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Article

Factor XI Deficiency Protects Against Atherogenesis in Apolipoprotein E/Factor XI Double Knockout Mice.

Arteriosclerosis, thrombosis, and vascular biology - 1 Mar 2016

Shnerb Ganor Reut, Harats Dror, Schiby Ginette, Gailani David, Levkovitz Hanna, Avivi Camila, Tamarin Ilia, Shaish Aviv, Salomon Ophira

Abstract excerpt

OBJECTIVE: Atherosclerosis and atherothrombosis are still major causes of mortality in the Western world, even after the widespread use of cholesterol-lowering medications. Recently, an association between local thrombin generation and atherosclerotic burden has been reported. Here, we studied the role of factor XI (FXI) deficiency in the process of atherosclerosis in mice. APPROACH AND RESULTS: Apolipoprotein...

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Source

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Identifiers

PMID: 26800563
DOI: 10.1161/ATVBAHA.115.306954
PMCID: PMC4785893

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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