Article
Use of Mouse Models in Atherosclerosis Research.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2015
Getz Godfrey S, Reardon Catherine A
Abstract excerpt
Cardiovascular disease is the major cause of death in most developed nations and the social and economic burden of this disease is quite high. Atherosclerosis is a major underlying basis for most cardiovascular diseases including myocardial infarction and stroke. Genetically modified mouse models, particularly mice deficient in apoprotein E or the LDL receptor, have been widely used in preclinical atherosclerosis...
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