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Article

Deficiency of glutathione peroxidase-1 accelerates the progression of atherosclerosis in apolipoprotein E-deficient mice.

Arteriosclerosis, thrombosis, and vascular biology - 1 Apr 2007

Torzewski Michael, Ochsenhirt Viola, Kleschyov Andrei L, Oelze Matthias, Daiber Andreas, Li Huige, Rossmann Heidi, Tsimikas Sotirios, Reifenberg Kurt, Cheng Fei, Lehr Hans-Anton, Blankenberg Stefan, Förstermann Ulrich, Münzel Thomas, Lackner Karl J

Abstract excerpt

BACKGROUND: We have recently demonstrated that activity of red blood cell glutathione peroxidase-1 is inversely associated with the risk of cardiovascular events in patients with coronary artery disease. The present study analyzed the effect of glutathione peroxidase-1 deficiency on atherogenesis in the apolipoprotein E-deficient mouse. METHODS AND RESULTS: Female apolipoprotein E-deficient mice with and without...

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PMID: 17255533
DOI: 10.1161/01.ATV.0000258809.47285.07

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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