Article
Gene expression profiling of asthma phenotypes demonstrates molecular signatures of atopy and asthma control.
The Journal of allergy and clinical immunology - 1 May 2016
Howrylak Judie A, Moll Matthew, Weiss Scott T, Raby Benjamin A, Wu Wei, Xing Eric P
Abstract excerpt
BACKGROUND: Recent studies have used cluster analysis to identify phenotypic clusters of asthma with differences in clinical traits, as well as differences in response to therapy with anti-inflammatory medications. However, the correspondence between different phenotypic clusters and differences in the underlying molecular mechanisms of asthma pathogenesis remains unclear. OBJECTIVE: We sought to determine...
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