Article
Classification of childhood asthma phenotypes and long-term clinical responses to inhaled anti-inflammatory medications.
The Journal of allergy and clinical immunology - 1 May 2014
Howrylak Judie A, Fuhlbrigge Anne L, Strunk Robert C, Zeiger Robert S, Weiss Scott T, Raby Benjamin A
Abstract excerpt
BACKGROUND: Although recent studies have identified the presence of phenotypic clusters in asthmatic patients, the clinical significance and temporal stability of these clusters have not been explored. OBJECTIVE: Our aim was to examine the clinical relevance and temporal stability of phenotypic clusters in children with asthma. METHODS: We applied spectral clustering to clinical data from 1041 children with...
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