Article
Cluster analysis and clinical asthma phenotypes.
American journal of respiratory and critical care medicine - 1 Aug 2008
Haldar Pranab, Pavord Ian D, Shaw Dominic E, Berry Michael A, Thomas Michael, Brightling Christopher E, Wardlaw Andrew J, Green Ruth H
Abstract excerpt
RATIONALE: Heterogeneity in asthma expression is multidimensional, including variability in clinical, physiologic, and pathologic parameters. Classification requires consideration of these disparate domains in a unified model. OBJECTIVES: To explore the application of a multivariate mathematical technique, k-means cluster analysis, for identifying distinct phenotypic groups. METHODS: We performed k-means cluster...
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