Article
Inflammatory phenotypes underlying uncontrolled childhood asthma despite inhaled corticosteroid treatment: rationale and design of the PACMAN2 study.
BMC pediatrics - 15 Jun 2013
Vijverberg Susanne J H, Koenderman Leo, van Erp Francine C, van der Ent Cornelis K, Postma Dirkje S, Brinkman Paul, Sterk Peter J, Raaijmakers Jan A M, Maitland-van der Zee Anke-Hilse
Abstract excerpt
BACKGROUND: The diagnosis of childhood asthma covers a broad spectrum of pathological mechanisms that can lead to similarly presenting clinical symptoms, but may nonetheless require different treatment approaches. Distinct underlying inflammatory patterns are thought to influence responsiveness to standard asthma medication. METHODS/DESIGN: The purpose of the PACMAN2 study is to identify inflammatory phenotypes...
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