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Article

Genetic profiles of transcriptomic clusters of childhood asthma determine specific severe subtype

14 May 2018

Abstract excerpt

Summary Background Previous studies have defined transcriptomic subtypes of adult asthma using samples of induced sputum and bronchial epithelium; however, those procedures are not readily applicable in the clinic, especially for childhood asthma. Objective We aim to dissect the transcriptomic clusters of childhood asthma using highly variably expressed genes of peripheral blood mononuclear cells (PBMC) among...

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PMID: 29758111
DOI: 10.1111/cea.13175

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