Article

A Network-based Deep Learning Framework Catalyzes GWAS and Multi-Omics Findings to Biology and Drug Repurposing for Alzheimer’s Disease

2021-10-21

Abstract excerpt

Human genome sequencing studies have identified numerous loci associated with complex diseases, including Alzheimer’s disease (AD). Translating human genetic findings (i.e., genome-wide association studies [GWAS]) to pathobiology and therapeutic discovery, however, remains a major challenge. To address this critical problem, we present a net work t opology-based deep learning framework to identify disease- a ss...

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Literature Corpus work: a305a6af-5094-54a0-af2d-af1817b99447
DOI: 10.1101/2021.10.20.465087

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