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Novel mutations conferring resistance to kanamycin in Mycobacterium tuberculosis clinical isolates from Northern India.

Tuberculosis (Edinburgh, Scotland) - 1 Jan 2016

Kaur Simerpreet, Rana Vibhuti, Singh Pooja, Trivedi Garima, Anand Shashi, Kaur Amanpreet, Gupta Pawan, Jain Amita, Sharma Charu

Abstract excerpt

Twenty-nine Kanamycin resistant clinical isolates of Mycobacterium tuberculosis from Northern India were screened to evaluate genetic mutations in rrs gene, eis gene with its promoter, and whiB7 gene along with its 5'UTR. 14 strains (~48.0%) collectively exhibited mutations in rrs, eis or whiB7 target regions. While the highest frequency of mutations was found in rrs gene, eis and whiB7 loci displayed novel...

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PMID: 26786660
DOI: 10.1016/j.tube.2015.10.012

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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