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Article

The role of eis mutations in the development of kanamycin resistance in Mycobacterium tuberculosis isolates from the Moscow region.

The Journal of antimicrobial chemotherapy - 1 Sept 2012

Gikalo Marina B, Nosova Elena Y, Krylova Ludmila Y, Moroz Arkadyi M

Abstract excerpt

OBJECTIVES: Kanamycin is an important second-line drug used to treat multidrug-resistant (MDR) tuberculosis (TB). Molecular analysis of the rrs gene seems to be not enough to identify every case of kanamycin resistance. In the present study we evaluated the incidence of eis mutations in kanamycin-resistant Mycobacterium tuberculosis isolates. METHODS: We analysed 70 MDR M. tuberculosis clinical isolates. All...

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Identifiers

PMID: 22593564
DOI: 10.1093/jac/dks178

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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