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Article

Evaluation of genetic mutations associated with Mycobacterium tuberculosis resistance to amikacin, kanamycin and capreomycin: a systematic review.

PloS one - 1 Jan 2012

Georghiou Sophia B, Magana Marisa, Garfein Richard S, Catanzaro Donald G, Catanzaro Antonino, Rodwell Timothy C

Abstract excerpt

BACKGROUND: Rapid molecular diagnostics for detecting multidrug-resistant and extensively drug-resistant tuberculosis (M/XDR-TB) primarily identify mutations in Mycobacterium tuberculosis (Mtb) genes associated with drug resistance. Their accuracy, however, is dependent largely on the strength of the association between a specific mutation and the phenotypic resistance of the isolate with that mutation, which is...

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Identifiers

PMID: 22479378
DOI: 10.1371/journal.pone.0033275
PMCID: PMC3315572

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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