Article
Sensory cell regeneration and stem cells: what we have already achieved in the management of deafness.
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology - 1 Sept 2008
Vlastarakos Petros V, Nikolopoulos Thomas P, Tavoulari Evangelia, Papacharalambous George, Tzagaroulakis Antonios, Dazert Stefan
Abstract excerpt
BACKGROUND/OBJECTIVE: Genetic manipulation of the cell-cycle exit, induction of new hair cells (HCs) through gene modification therapy, and introduction of stem cells (SCs) into damaged cochleas potentially offer exciting new strategies in treating sensorineural hearing loss. MATERIALS AND METHODS: Literature review from Medline and database sources. STUDY SELECTION: Ex vivo models, animal studies, in vitro...
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