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Article

Sox2 is required for sensory organ development in the mammalian inner ear.

Nature - 21 Apr 2005

Kiernan Amy E, Pelling Anna L, Leung Keith K H, Tang Anna S P, Bell Donald M, Tease Charles, Lovell-Badge Robin, Steel Karen P, Cheah Kathryn S E

Abstract excerpt

Sensory hair cells and their associated non-sensory supporting cells in the inner ear are fundamental for hearing and balance. They arise from a common progenitor, but little is known about the molecular events specifying this cell lineage. We recently identified two allelic mouse mutants, light coat and circling (Lcc) and yellow submarine (Ysb), that show hearing and balance impairment. Lcc/Lcc mice are...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15846349
DOI: 10.1038/nature03487

Genes

SOX2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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