Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Polygenic risk score prediction of antipsychotic dosage in schizophrenia.

Schizophrenia research - 1 Feb 2016

Hettige Nuwan C, Cole Christopher B, Khalid Sarah, De Luca Vincenzo

Abstract excerpt

OBJECTIVE: Genetic variants have yet to be identified as reliable predictors of antipsychotic dosage. The purpose of this study is to quantify significant genetic risk variants prioritized from the Psychiatric GWAS Consortium (PGC2) study for schizophrenia as a polygenic score to test our hypothesis that it may represent symptom severity in patients and therefore predict antipsychotic dosage. METHODS:...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antipsychotic Agents
Share to Genetic Loci
Share to Interview, Psychological

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Multifactorial Inheritance

Share to Psychotic Disorders

Share to Risk Assessment

Share to Schizophrenia

Share to Severity of Illness Index

Source

Identifiers

PMID: 26778674
DOI: 10.1016/j.schres.2015.12.015

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Polygenic risk score prediction of antipsychotic dosage in schizophrenia.PMID 26778674Read ↗

Polygenic Liability for Antipsychotic Dosage and Polypharmacy - A Real-World Registry and Biobank StudySemantic proximity Read ↗

Candidate gene analysis of pharmacodynamic targets for antipsychotic dosage.Semantic proximity Read ↗

Genome-wide association analysis to predict optimal antipsychotic dosage in schizophrenia: a pilot study.Semantic proximity Read ↗

Schizophrenia Polygenic Risk Score as a Predictor of Antipsychotic Efficacy in First-Episode PsychosisSemantic proximity Read ↗

Use of candidate gene markers to guide antipsychotic dosage adjustment.Semantic proximity Read ↗

Prediction of antipsychotics efficacy based on a polygenic risk score: a real-world cohort studySemantic proximity Read ↗

Pharmacogenomic scores in psychiatry: Systematic review of existing evidenceSemantic proximity Read ↗

A Systematic Review and Analysis of the Use of Polygenic Scores in Pharmacogenomics.Semantic proximity Read ↗

Genomic stratification of clozapine prescription patterns using schizophrenia polygenic scoresSemantic proximity Read ↗

Polygenic risk score analyses of symptoms and treatment response in an antipsychotic-naive first episode of psychosis cohort.Semantic proximity Read ↗

Associations Between Polygenic Risk Score Loading, Psychosis Liability, and Clozapine Use Among Individuals With SchizophreniaSemantic proximity Read ↗

The use of polygenic risk scores to identify phenotypes associated with genetic risk of schizophrenia: Systematic review.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.