Article
Use of candidate gene markers to guide antipsychotic dosage adjustment.
Progress in neuro-psychopharmacology & biological psychiatry - 3 Oct 2014
Hettige Nuwan C, Zai Clement, Hazra Monica, Borlido Carol, Kennedy James L, Strauss John, Le Foll Bernard, Wong Albert, Remington Gary, De Luca Vincenzo
Abstract excerpt
OBJECTIVE: To improve antipsychotic treatment in schizophrenia patients, many studies have investigated genetic polymorphisms associated with antipsychotic metabolizing enzymes and receptors. While these studies have typically focused on drug response, few have investigated genetic influences on antipsychotic dosage. This study set out to analyze the association between 134 SNPs in 38 candidate genes and...
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