Article
Genome-wide association analysis to predict optimal antipsychotic dosage in schizophrenia: a pilot study.
Journal of neural transmission (Vienna, Austria : 1996) - 1 Mar 2016
Koga Arthur T, Strauss John, Zai Clement, Remington Gary, De Luca Vincenzo
Abstract excerpt
In recent years, several studies have investigated genetic polymorphisms of antipsychotic drug-metabolizing enzymes and receptors. However, most studies focused on drug response and very few have investigated the genetic influence on antipsychotic dosage. The aim of the present study is to test the association between antipsychotic dosages at genome-wide level. The current dosage of antipsychotic medications was...
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