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Article

Variation analysis of EXO1 gene in Chinese patients with premature ovarian failure.

Reproductive biomedicine online - 1 Mar 2016

Su Shizhen, Han Ting, Ma Bowen, Li Weiping, Qin Yingying, Zhao Shidou, Chen Zi-Jiang

Abstract excerpt

Exonuclease 1 (EXO1) is required for both DNA repair and meiosis. Inactivation of EXO1 gene in mice leads to infertility. This study aimed to investigate whether variants in the EXO1 gene contribute to human premature ovarian failure (POF). The coding region of EXO1 was sequenced in 186 Han Chinese patients with non-syndromic POF. No plausible mutation was detected. The results suggest that mutations in the...

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Source

Identifiers

PMID: 26774993
DOI: 10.1016/j.rbmo.2015.12.003

Genes

EXO1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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