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Article

The screening of HELQ gene in Chinese patients with premature ovarian failure.

Reproductive biomedicine online - 1 Oct 2015

Wang Wenting, Zhao Shidou, Zhuang Lili, Li Weiping, Qin Yingying, Chen Zi-Jiang

Abstract excerpt

HELQ, a member of DNA repair gene family, is an enzyme required for DNA strands cross-links repair and closely related to age at natural menopause. It also possesses a critical role in the germ cell maintenance, and loss of HELQ gene leads to subfertility. The aim of the present study was to investigate whether mutations in HELQ contribute to premature ovarian failure (POF) in Chinese women. A cohort of 192...

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Identifiers

PMID: 26190809
DOI: 10.1016/j.rbmo.2015.06.012

Genes

HELQ

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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