Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Analysis of LHX8 mutation in premature ovarian failure.

Fertility and sterility - 1 Apr 2008

Qin Yingying, Zhao Han, Kovanci Ertug, Simpson Joe Leigh, Chen Zi-Jiang, Rajkovic Aleksandar

Abstract excerpt

The LHX8 (LIM homeobox 8) gene encodes a LIM homeodomain transcriptional regulator that is preferentially expressed in germ cells and critical for mammalian oogenesis. The authors investigated whether nucleotide changes were present in the LHX8 gene of Caucasian women with premature ovarian failure (POF), as compared with control women. When the authors sequenced 95 Caucasian women with POF, they discovered two...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 3' Untranslated Regions
Share to Case-Control Studies
Share to Homeodomain Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Introns

Share to LIM-Homeodomain Proteins

Share to Primary Ovarian Insufficiency

Share to Transcription Factors

Share to White People

Source

Open in PubMed Open full text

Identifiers

PMID: 17624344
DOI: 10.1016/j.fertnstert.2007.04.017
PMCID: PMC2680741

Genes

LHX8

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Analysis of LHX8 mutation in premature ovarian failure.PMID 17624344Read ↗

New insights into the genetic basis of premature ovarian insufficiency: Novel causative variants and candidate genes revealed by genomic sequencingSemantic proximity Read ↗

Association of 8q22.3 locus in Chinese Han with idiopathic premature ovarian failure (POF).Semantic proximity Read ↗

NOBOX homeobox mutation causes premature ovarian failure.Semantic proximity Read ↗

Mutation analysis of NANOS3 in 80 Chinese and 88 Caucasian women with premature ovarian failure.Semantic proximity Read ↗

Homozygous variants in SYCP2L cause premature ovarian insufficiency.Semantic proximity Read ↗

Novel loss‐of‐function mutation in MCM8 causes premature ovarian insufficiencySemantic proximity Read ↗

Identification of novel mutations in FOXL2 associated with premature ovarian failure.Semantic proximity Read ↗

Mutation analysis of NOBOX homeodomain in Chinese women with premature ovarian failure.Semantic proximity Read ↗

Penetrance of pathogenic genetic variants associated with premature ovarian insufficiencySemantic proximity Read ↗

Searching for the 'X' factor: investigating the genetics of primary ovarian insufficiency.Semantic proximity Read ↗

Association of FOXL2 and ERCC6 variants with premature ovarian insufficiency and their potential use in clinical IVF guidance.Semantic proximity Read ↗

Novel variants in the SOHLH2 gene are implicated in human premature ovarian failure.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.