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Article

Mutation analysis of NOBOX homeodomain in Chinese women with premature ovarian failure.

Fertility and sterility - 1 Apr 2009

Qin Yingying, Shi Yuhua, Zhao Yueran, Carson Sandra Ann, Simpson Joe Leigh, Chen Zi-Jiang

Abstract excerpt

The newborn ovary homeobox gene (NOBOX) is an oocyte-specific homeobox gene that plays a critical role in early folliculogenesis, thus representing an attractive candidate gene for nonsyndromic ovarian failure. We investigated whether perturbation in the homeodomain region of NOBOX was present in Chinese women with premature ovarian failure (POF). We sequenced 200 Chinese patients with POF, and discovered only...

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Identifiers

PMID: 18930203
DOI: 10.1016/j.fertnstert.2008.08.020

Genes

NOBOX

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Mutation analysis of NOBOX homeodomain in Chinese women with premature ovarian failure.PMID 18930203Read ↗

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Analysis of LHX8 mutation in premature ovarian failure.Semantic proximity Read ↗

Identification of Two Novel Missense Variants in BNC1 in Han Chinese Patients With Non-syndromic Premature Ovarian Insufficiency.Semantic proximity Read ↗

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