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Article

Whole-exome sequencing reveals new potential genes and variants in patients with premature ovarian insufficiency.

Journal of assisted reproduction and genetics - 1 Mar 2022

Turkyilmaz Ayberk, Alavanda Ceren, Ates Esra Arslan, Geckinli Bilgen Bilge, Polat Hamza, Gokcu Mehmet, Karakaya Taner, Cebi Alper Han, Soylemez Mehmet Ali, Guney Ahmet İlter, Ata Pinar, Arman Ahmet

Abstract excerpt

PURPOSE: Premature ovarian insufficiency (POI) is a heterogeneous disorder characterized by the cessation of menstrual cycles before the age of 40 years due to the depletion or dysfunction of the ovarian follicles. POI is a highly heterogeneous disease in terms of etiology. The aim of this study is to reveal the genetic etiology in POI patients. METHODS: A total of 35 patients (mean age: 27.2 years) from 28...

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Share to Chromosome Aberrations
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Fragile X Mental Retardation Protein

Share to Karyotyping

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Share to Ovarian function and disorders

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Share to Reproductive Biology and Fertility

Source

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Identifiers

PMID: 35066699
DOI: 10.1007/s10815-022-02408-0
PMCID: PMC8995228

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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