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Article

Potentially functional polymorphisms of EXO1 and risk of lung cancer in a Chinese population: A case-control analysis.

Lung cancer (Amsterdam, Netherlands) - 1 Jun 2008

Jin Guangfu, Wang Haifeng, Hu Zhibin, Liu Hongliang, Sun Weiwei, Ma Hongxia, Chen Dan, Miao Ruifen, Tian Tian, Jin Li, Wei Qingyi, Huang Wei, Lu Daru, Shen Hongbing

Abstract excerpt

Exonuclease 1 (EXO1) is an important nucleases involved in mismatch repair system that contributes to maintain genomic stability, to modulate DNA recombination, and to mediate cell cycle arrest. Potentially functional polymorphisms in EXO1 may alter cancer risks by influencing the repair activity of EXO1. Therefore, we hypothesized that single nucleotide polymorphisms (SNPs) in EXO1 were associated with risk of...

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Asian People
Carcinoma, Non-Small-Cell Lung
Carcinoma, Small Cell
Case-Control Studies
DNA Repair

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 18079015
DOI: 10.1016/j.lungcan.2007.11.003

Genes

EXO1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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