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Article

Fluid Flow Regulation of Revascularization and Cellular Organization in a Bioengineered Liver Platform.

Tissue engineering. Part C, Methods - 1 Mar 2016

Baptista Pedro M, Moran Emma C, Vyas Dipen, Ribeiro Maria H, Atala Anthony, Sparks Jessica L, Soker Shay

Abstract excerpt

OBJECTIVE: Modeling of human liver development, especially cellular organization and the mechanisms underlying it, is fundamental for studying liver organogenesis and congenital diseases, yet there are no reliable models that mimic these processes ex vivo. DESIGN: Using an organ engineering approach and relevant cell lines, we designed a perfusion system that delivers discrete mechanical forces inside an...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26772270
DOI: 10.1089/ten.TEC.2015.0334
PMCID: PMC4863717

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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