Article

Computational fluid dynamics enables predictable scale-up of perfusion bioreactors for microvessel production

2026-03-26

Abstract excerpt

Scaling up microvessel culture systems is essential for producing vascularized clinically relevant tissues, yet current platforms offer little guidance on how to preserve flow conditions during scale-up. Here, we present a computational–experimental framework using computational fluid dynamics (CFD) to guide the design and scaling of microvessel bioreactors. Interstitial flow distributions were pre-dicted in two p...

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Literature Corpus work: 65121620-7bf0-5cb2-a0fa-84dc52d70b21
DOI: 10.64898/2026.03.24.713992

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