Article

Remodeling of self-assembled microvascular networks under long term flow

2025-03-18

Abstract excerpt

The incorporation of a functional perfusable microvascular network (MVN) is a common requirement for most organ on-chip-models. Long-term perfusion of MVNs is often required for the maturation of organ phenotypes and disease pathologies and to model the transport of cells and drugs entering organs. In our microphysiological system, we observe that flow can recover perfusion in regressed MVNs and maintain perfusabl...

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Literature Corpus work: 38c1a1d0-693f-5971-960e-52e00c32c4c7
DOI: 10.1101/2025.03.17.643791

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