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Article

Effect of biochemical and biomechanical factors on vascularization of kidney organoid-on-a-chip

8 Nov 2021

Abstract excerpt

Kidney organoids derived from the human pluripotent stem cells (hPSCs) recapitulating human kidney are the attractive tool for kidney regeneration, disease modeling, and drug screening. However, the kidney organoids cultured by static conditions have the limited vascular networks and immature nephron-like structures unlike human kidney. Here, we developed a kidney organoid-on-a-chip system providing fluidic flow...

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PMID: 34748091
DOI: 10.1186/s40580-021-00285-4

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