Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A vascularized model of the human liver mimics regenerative responses

28 Jun 2022

Abstract excerpt

Liver regeneration is a well-orchestrated process that is typically studied in animal models. Although previous animal studies have offered many insights into liver regeneration, human biology is less well understood. To this end, we developed a three-dimensional (3D) platform called structurally vascularized hepatic ensembles for analyzing regeneration (SHEAR) to model multiple aspects of human liver...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Liver physiology and pathology
Share to Organ Transplantation Techniques and Outcomes
Share to Tissue Engineering and Regenerative Medicine

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35763565
DOI: 10.1073/pnas.2115867119

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A vascularized model of the human liver mimics regenerative responsesPMID 35763565Read ↗

Multi-cellular 3D human primary liver cell culture elevates metabolic activity under fluidic flowSemantic proximity Read ↗

A microvascularized <i>in vitro</i> liver model for disease modeling and drug discoverySemantic proximity Read ↗

Advances in 3D cell culture for liver preclinical studies.Semantic proximity Read ↗

Bioartificial Liver: A Brief IntroductionSemantic proximity Read ↗

Cell atlas of the regenerating human liver after portal vein embolizationSemantic proximity Read ↗

Angiocrine signaling in the hepatic sinusoids in health and disease.Semantic proximity Read ↗

Self-organized vascularized human liver spheroids: Serum-free culture conditions and use as tissue building blocksSemantic proximity Read ↗

Recapitulation of clinical and molecular hallmarks of lipid-induced hepatic insulin resistance in a zonated, vascularized human liver acinus microphysiological system during metabolic dysfunction-associated steatotic liver disease (MASLD) progressionSemantic proximity Read ↗

Cyclic mechanical stretching stimuli promotes angiocrine signals during <i>in vitro</i> liver bud formation from human pluripotent stem cellsSemantic proximity Read ↗

Enhanced Maturity and Functionality of Vascularized Human Liver Organoids through 3D Bioprinting and Pillar Plate CultureSemantic proximity Read ↗

Advances in bioartificial liver devices.Semantic proximity Read ↗

A MICROFLUIDIC DEVICE FOR LONG-TERM MAINTENANCE OF ORGANOTYPIC LIVER CULTURESSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.