Article
Key genes involved in the immune response are generally not associated with intraprostatic inflammation in men without a prostate cancer diagnosis: Results from the prostate cancer prevention trial.
The Prostate - 1 May 2016
Winchester Danyelle A, Gurel Bora, Till Cathee, Goodman Phyllis J, Tangen Catherine M, Santella Regina M, Johnson-Pais Teresa L, Leach Robin J, Thompson Ian M, Xu Jianfeng, Zheng S Lilly, Lucia M Scott, Lippman Scott M, Parnes Howard L, Isaacs William B, Drake Charles G, De Marzo Angelo M, Platz Elizabeth A
Abstract excerpt
BACKGROUND: We previously reported that both intraprostatic inflammation and SNPs in genes involved in the immune response are associated with prostate cancer risk and disease grade. In the present study, we evaluated the association between these SNPs and intraprostatic inflammation in men without a prostate cancer diagnosis. METHODS: Included in this cross-sectional study were 205 white controls from a...
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