Article
A Prospective Study of Chronic Inflammation in Benign Prostate Tissue and Risk of Prostate Cancer: Linked PCPT and SELECT Cohorts.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Oct 2017
Platz Elizabeth A, Kulac Ibrahim, Barber John R, Drake Charles G, Joshu Corinne E, Nelson William G, Lucia M Scott, Klein Eric A, Lippman Scott M, Parnes Howard L, Thompson Ian M, Goodman Phyllis J, Tangen Catherine M, De Marzo Angelo M
Abstract excerpt
Background: We leveraged two trials to test the hypothesis of an inflammation-prostate cancer link prospectively in men without indication for biopsy.Methods: Prostate Cancer Prevention Trial (PCPT) participants who had an end-of-study biopsy performed per protocol that was negative for cancer and who subsequently enrolled in the Selenium and Vitamin E Cancer Prevention Trial (SELECT) were eligible. We selected...
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