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Article

Association of IL10 and other immune response- and obesity-related genes with prostate cancer in CLUE II.

The Prostate - 1 Jun 2009

Wang Ming-Hsi, Helzlsouer Kathy J, Smith Michael W, Hoffman-Bolton Judith A, Clipp Sandra L, Grinberg Viktoriya, De Marzo Angelo M, Isaacs William B, Drake Charles G, Shugart Yin Yao, Platz Elizabeth A

Abstract excerpt

BACKGROUND: Chronic intra-prostatic inflammation and obesity are thought to influence prostate carcinogenesis. Thus, variants in genes in these pathways could be associated with prostate cancer risk. METHODS: We genotyped 17 common single nucleotide polymorphisms (SNPs) in RNASEL, TLR4, IL1B, IL6, IL8, IL10, TNF, CRP, ADIPOQ, LEP, PPARG, and TCF7L2 in 258 white prostate cancer cases and 258 matched controls...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19267370
DOI: 10.1002/pros.20933
PMCID: PMC3016874

Genes

TLR4
CRP
ADIPOQ
LEP
PPARG
RNASEL
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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