Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Interleukin-6 promoter variants, prostate cancer risk, and survival.

The Prostate - 1 Dec 2012

Tindall Elizabeth A, Severi Gianluca, Hoang Hoa N, Southey Melissa C, English Dallas R, Hopper John L, Giles Graham G, Hayes Vanessa M

Abstract excerpt

BACKGROUND: Inflammation has been implicated in prostate cancer (PCa) pathogenesis. Promoter DNA variants responsible for differential expression of key cytokines may therefore influence susceptibility to PCa. METHODS: Two interleukin-6 (IL-6) promoter variants, -174G>C and -6331T>C, were genotyped for association with PCa risk and survival using the Risk Factors for Prostate Cancer Study (RFPCS, 825 cases and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Alleles
Share to Interleukin-6

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Polymorphism, Single Nucleotide

Share to Promoter Regions, Genetic

Share to Prostatic Neoplasms

Share to Risk Factors

Share to Survival Rate

Source

Identifiers

PMID: 22782910
DOI: 10.1002/pros.22557

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Interleukin-6 promoter variants, prostate cancer risk, and survival.PMID 22782910Read ↗

Interleukin-6 gene -174G>C and -636G>C promoter polymorphisms and prostate cancer risk.Semantic proximity Read ↗

-174G/C polymorphism in the interleukin-6 promoter is differently associated with prostate cancer incidence depending on race.Semantic proximity Read ↗

Comprehensive analysis of the cytokine-rich chromosome 5q31.1 region suggests a role for IL-4 gene variants in prostate cancer risk.Semantic proximity Read ↗

Interleukins-6 -174G/C (rs1800795) and -572C/G (rs1800796) polymorphisms and prostate cancer risk.Semantic proximity Read ↗

Genetic polymorphisms in inflammation pathway genes and prostate cancer risk.Semantic proximity Read ↗

The interleukin-6 -174G/C polymorphism and prostate cancer risk: a systematic review and meta-analysis.Semantic proximity Read ↗

Interleukin-6 -572G/C polymorphism and prostate cancer susceptibility.Semantic proximity Read ↗

An Interleukin-6 Single Nucleotide Polymorphism and Susceptibility to Prostate Adenocarcinoma and Bone Metastasis in an Iranian PopulationSemantic proximity Read ↗

C-reactive protein, interleukin-6, and prostate cancer risk in men aged 65 years and older.Semantic proximity Read ↗

Association between -174 G/C promoter polymorphism of the interleukin-6 gene and progression of prostate cancer in North Indian population.Semantic proximity Read ↗

Interactions of cytokine gene polymorphisms in prostate cancer risk.Semantic proximity Read ↗

IL-10 polymorphisms and prostate cancer risk: a meta-analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.