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Article

CHRNA5/CHRNA3 Locus Associates with Increased Mortality among Smokers.

COPD - 1 Aug 2016

Kupiainen Henna, Kuokkanen Mikko, Kontto Jukka, Virtamo Jarmo, Salomaa Veikko, Lindqvist Ari, Kilpeläinen Maritta, Laitinen Tarja

Abstract excerpt

Polymorphisms in the nicotinic acetylcholine receptor gene (CHRNA5/CHRNA3 locus) have been associated with several smoking related traits such as nicotine dependence, cigarette consumption, smoking cessation, lung cancer, and COPD. The aim of this candidate gene study was to study the locus among the Finnish COPD patients and long-term smokers with regard to COPD risk, smoking behavior, cancer, and all-cause...

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Source

Identifiers

PMID: 26751916
DOI: 10.3109/15412555.2015.1049260

Genes

CHRNA3
CHRNA5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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