Nicotinic acetylcholine receptor polymorphism, smoking behavior, and tobacco-related cancer and lung and cardiovascular diseases: a cohort study.

doi:10.1200/JCO.2010.32.9870

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Article

Nicotinic acetylcholine receptor polymorphism, smoking behavior, and tobacco-related cancer and lung and cardiovascular diseases: a cohort study.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 20 Jul 2011

Kaur-Knudsen Diljit, Bojesen Stig E, Tybjærg-Hansen Anne, Nordestgaard Børge G

Abstract excerpt

PURPOSE: We examined the associations between the nicotinic acetylcholine receptor polymorphism (rs1051730) on chromosome 15q25 marking the gene cluster CHRNA3-CHRNB4-CHRNA5, smoking behavior, and tobacco-related cancer and lung and cardiovascular diseases in the general population. METHODS: Ten thousand three hundred thirty participants from the Copenhagen City Heart Study were genotyped and observed...

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Identifiers

PMID: 21646606
DOI: 10.1200/JCO.2010.32.9870

Genes

CHRNA3
CHRNA5
CHRNB4

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Nicotinic acetylcholine receptor polymorphism, smoking behavior, and tobacco-related cancer and lung and cardiovascular diseases: a cohort study.PMID 21646606Read ↗

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