Article
CHRNA3 genotype, nicotine dependence, lung function and disease in the general population.
The European respiratory journal - 1 Dec 2012
Kaur-Knudsen Diljit, Nordestgaard Børge G, Bojesen Stig E
Abstract excerpt
The CHRNA3 rs1051730 polymorphism has been associated to chronic obstructive pulmonary disease (COPD), lung cancer and nicotine dependence in case-control studies with high smoking exposure; however, its influence on lung function and COPD severity in the general population is largely unknown. We genotyped 57,657 adult individuals from the Copenhagen General Population Study, of whom 34,592 were ever-smokers....
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