Article
A functional polymorphism in the CHRNA3 gene and risk of chronic obstructive pulmonary disease in a Korean population.
Journal of Korean medical science - 1 Dec 2012
Lee Jae Yeon, Yoo Seung Soo, Kang Hyo-Gyoung, Jin Guang, Bae Eun Young, Choi Yi Young, Choi Jin Eun, Jeon Hyo-Sung, Lee Jaehee, Lee Shin Yup, Cha Seung-Ick, Kim Chang Ho, Park Jae Yong
Abstract excerpt
A genome-wide association study has identified the 15q25 region as being associated with the risk of chronic obstructive pulmonary disease (COPD) in Caucasians. This study intended as a confirmatory assessment of this association in a Korean population. The rs6495309C > T polymorphism in the promoter of nicotinic acetylcholine receptor alpha subunit 3 (CHRNA3) gene was investigated in a case-control study that...
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