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Article

Evidence for redox sensing by a human cardiac calcium channel.

Scientific reports - 11 Jan 2016

Muralidharan Padmapriya, Cserne Szappanos Henrietta, Ingley Evan, Hool Livia

Abstract excerpt

Ion channels are critical to life and respond rapidly to stimuli to evoke physiological responses. Calcium influx into heart muscle occurs through the ion conducting α1C subunit (Cav1.2) of the L-type Ca(2+) channel. Glutathionylation of Cav1.2 results in increased calcium influx and is evident in ischemic human heart. However controversy exists as to whether direct modification of Cav1.2 is responsible for...

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Source

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Identifiers

PMID: 26750869
DOI: 10.1038/srep19067
PMCID: PMC4707475

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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