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Article

Quantitation of the calcium and membrane binding properties of the C2 domains of dysferlin.

Biophysical journal - 21 Jan 2014

Abdullah Nazish, Padmanarayana Murugesh, Marty Naomi J, Johnson Colin P

Abstract excerpt

Dysferlin is a large membrane protein involved in calcium-triggered resealing of the sarcolemma after injury. Although it is generally accepted that dysferlin is Ca(2+) sensitive, the Ca(2+) binding properties of dysferlin have not been characterized. In this study, we report an analysis of the Ca(2+) and membrane binding properties of all seven C2 domains of dysferlin as well as a multi-C2 domain construct....

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Source

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Identifiers

PMID: 24461013
DOI: 10.1016/j.bpj.2013.11.4492
PMCID: PMC3907215

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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