Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cellular responses to protein overload: key event in renal disease progression.

Current opinion in nephrology and hypertension - 1 Jan 2004

Zoja Carla, Benigni Ariela, Remuzzi Giuseppe

Abstract excerpt

PURPOSE OF REVIEW: Insight into the mechanisms underlying the progression of chronic proteinuric nephropathies has attracted the interest of the renal community in the last two decades. Systemic hypertension, proteinuria, cytokines and growth factors, and reactive oxygen species have all been implicated. Reviewed here are the determinants of tubulointerstitial injury; the focus is on protein ultrafiltration and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Disease Progression
Share to Fibrosis
Share to Kidney Diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Kidney Tubules

Share to Phenotype

Share to Proteins

Share to Signal Transduction

Source

Identifiers

PMID: 15090857
DOI: 10.1097/00041552-200401000-00005

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cellular responses to protein overload: key event in renal disease progression.PMID 15090857Read ↗

Mechanisms of progression of chronic kidney disease.Semantic proximity Read ↗

Progression of Tubulointerstitial Fibrosis and the Chronic Kidney Disease Phenotype – Role of Risk Factors and EpigeneticsSemantic proximity Read ↗

Renal interstitial fibrosis: mechanisms and evaluation.Semantic proximity Read ↗

Hypertension and kidneys: unraveling complex molecular mechanisms underlying hypertensive renal damage.Semantic proximity Read ↗

Mechanisms of tubulointerstitial fibrosis.Semantic proximity Read ↗

TGF-β1/p53 signaling in renal fibrogenesis.Semantic proximity Read ↗

The proximal tubule in the pathophysiology of the diabetic kidney.Semantic proximity Read ↗

Inflammation in Areas of Fibrosis Precedes Loss of Kidney Function in Lupus NephritisSemantic proximity Read ↗

Microarray and Bioinformatics Analysis of Gene Expression in Experimental Membranous NephropathySemantic proximity Read ↗

Cellular mediators of renal vascular dysfunction in hypertension.Semantic proximity Read ↗

The aging kidney is characterized by tubuloinflammaging, a phenotype associated with MHC-II gene expression.Semantic proximity Read ↗

[Mechanisms of repair after renal injury].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.