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Article

L10P mutation in DJ-1 gene induced oxidative stress and mitochondrial disfunction.

Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences - 1 Dec 2015

Guo Jifeng, He Dan, Wang Lei, Kang Jifeng, Li Nan, Yan Xinxiang, Tang Beisha

Abstract excerpt

OBJECTIVE: To investigate the effect of the L10P mutation on the cellular mitochondrial disfunction. METHODS: Spectrophotometer, flow cytometry and electron microscope was utilized to examine cell viability, reactive oxygen species (ROS), mitochondrial transmembrane potential, complex I activity and mitochondrial morphous of the HEK293 monoclone cell lines, in which wild-type and L10P mutant DJ-1 protein are...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 26739068
DOI: 10.11817/j.issn.1672-7347.2015.12.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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