Article
Importance of mitochondrial dysfunction in oxidative stress response: A comparative study of gene expression profiles
11 Mar 2011
Abstract excerpt
Mitochondria are considered to play an important role in oxidative stress response since they are a source of reactive oxygen species and are also targeted by these species. This study examined the mitochondrial conditions in cells of epithelial origin that were exposed to H(2)O(2) and found a decline in the membrane potential along with a specific loss of UQCRC1, a sub-unit of complex III, suggesting that...
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