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Article

No obvious phenotypic abnormalities in mice lacking the Pate4 gene.

Biochemical and biophysical research communications - 22 Jan 2016

Heckt Timo, Keller Johannes, Reusch Roswitha, Hartmann Kristin, Krasemann Susanne, Hermans-Borgmeyer Irm, Amling Michael, Schinke Thorsten

Abstract excerpt

We have previously reported that the hormone calcitonin (CT) negatively regulates bone formation by inhibiting the release of sphingosine-1-phosphate from bone-resorbing osteoclasts. In the context of this study we additionally observed that CT repressed the expression of Pate4, encoding the secreted protein caltrin/Svs7, in osteoclasts from wildtype mice. To assess a possible function of Pate4 in bone...

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Identifiers

PMID: 26731031
DOI: 10.1016/j.bbrc.2015.12.104

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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