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Article

Male sexual dysfunction in mice bearing targeted mutant alleles of the PEA3 ets gene.

Molecular and cellular biology - 1 Dec 2000

Laing M A, Coonrod S, Hinton B T, Downie J W, Tozer R, Rudnicki M A, Hassell J A

Abstract excerpt

PEA3, a member of the Ets family of transcriptional regulatory proteins, is expressed in a unique spatial and temporal pattern during mouse embryogenesis; its overexpression is positively correlated with HER2-mediated breast tumorigenesis in both humans and mice. To determine whether PEA3 plays a part in development and oncogenesis and to uncover its normal physiological role, we generated mice lacking functional...

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Identifiers

PMID: 11094084
DOI: 10.1128/MCB.20.24.9337-9345.2000
PMCID: PMC102190

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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