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Article

Loss of all 3 Extended Synaptotagmins does not affect normal mouse development, viability or fertility.

Cell cycle (Georgetown, Tex.) - 1 Sept 2016

Tremblay Michel G, Moss Tom

Abstract excerpt

The extended synaptotagmins, E-Syt1, 2 and 3, are multiple C2 domain membrane proteins that are tethered to the endoplasmic reticulum and interact in a calcium dependent manner with plasma membrane phospholipids to form endoplasmic reticulum - plasma membrane junctions. These junctions have been implicated in the exchange of phospholipids between the 2 organelles. The E-Syts have further been implicated in...

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Identifiers

PMID: 27399837
DOI: 10.1080/15384101.2016.1203494
PMCID: PMC5004701

Genes

STIM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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