Article
Genetic polymorphisms and novel allelic variants of CYP2C19 in the Chinese Han population.
Pharmacogenomics - 1 Nov 2012
Hu Li-Ming, Dai Da-Peng, Hu Guo-Xin, Yang Jie-Fu, Xu Ren-Ai, Yang Li-Ping, Qian Jian-Chang, Ge Ren-Shan, Cai Jian-Ping
Abstract excerpt
AIM: This study aims to systematically investigate the genetic polymorphisms of the CYP2C19 gene and provide accurate data of the allele distribution pattern in the Chinese Han population. MATERIALS & METHODS: We amplified all nine exons of the CYP2C19 gene in 2127 unrelated healthy Chinese Han subjects from two geographical locations (Zhejiang province, n = 1127; Hebei province, n = 1000), using direct...
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