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Article

Characterizing gene-gene interactions in a statistical epistasis network of twelve candidate genes for obesity

1 Jun 2015

Abstract excerpt

BACKGROUND: Recent findings have reemphasized the importance of epistasis, or gene-gene interactions, as a contributing factor to the unexplained heritability of obesity. Network-based methods such as statistical epistasis networks (SEN), present an intuitive framework to address the computational challenge of studying pairwise interactions between thousands of genetic variants. In this study, we aimed to analyze...

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PMID: 26715945
DOI: 10.1186/s13040-015-0077-x

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